WELCOME TO THE RISQUES LAB
Department of Laboratory Medicine and Pathology, University of Washington
CANCER AND AGING / SOMATIC MUTATIONS / EARLY CANCER DETECTION
Cancer is a disease of aging driven by somatic mutations. At the Risques lab, we use ultra-deep sequencing to study how somatic mutations accumulate with aging and how they contribute to cancer development. In addition to somatic mutations, we are also interested in other genetic alterations that contribute to aging and cancer including telomere shortening and mitochondrial dysfunction. Our goal is to explore the link between cancer and aging and to investigate the genetic alterations that drive the early steps of human carcinogenesis in order to design better tools for early cancer detection, prediction, and risk assessment.